Methods for Differentiating Prion Types in Food-Producing Animals
نویسندگان
چکیده
منابع مشابه
Methods for Differentiating Prion Types in Food-Producing Animals
Prions are an enigma amongst infectious disease agents as they lack a genome yet confer specific pathologies thought to be dictated mainly, if not solely, by the conformation of the disease form of the prion protein (PrP(Sc)). Prion diseases affect humans and animals, the latter including the food-producing ruminant species cattle, sheep, goats and deer. Importantly, it has been shown that the ...
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Transmissible spongiform encephalopathies (TSEs), or prion diseases, represent a unique form of infectious disease based on misfolding of a self-protein (PrP(C)) into a pathological, infectious conformation (PrP(Sc)). Prion diseases of food animals gained notoriety during the bovine spongiform encephalopathy (BSE) outbreak of the 1980s. In particular, disease transmission to humans, to the gene...
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ژورنال
عنوان ژورنال: Biology
سال: 2015
ISSN: 2079-7737
DOI: 10.3390/biology4040785